- Finding topical or oral drugs that can modify or ‘read through’ certain types of mutations in EB
- Discovering drugs that can increase or decrease the activity of genes
- Repurpose drugs to reduce fibrotic effect, or treat skin cancer
Aggressive and usually fatal skin cancers develop in areas of scarring and chronic wounds.
Losartan – Trial information Article
Rigosertib – Information on this debra-funded research project
Nivolumab – More information on the use of this monoclonal antibody in RDEB skin cancers (University of Salzburg)