cure-eb.org

Research Overview

Our mission is to find a cure for EB.

Our research in centred around this goal.

Our strategy is focused research around developing treatments to provide symptomatic relief, quality of life change and those projects aiming to cure the condition

The range of EB related mutations within the three main subtypes, giving rise to a variety of severities, means there will not be a single cure for EB. Within each EB type there will be need to be a combination of therapies designed to meet the particular needs of an individual patient.

EBSTEM Trial photo

Children on the EBSTEM trial

Our research strategy

Aim to correct or replace the genetic fault that causes the condition and manage the consequences of that fault

By

– Funding translational research

– Exploring innovative research opportunities from other fields and conditions

– Encouraging collaboration between academics and academic institutions, research funding organisations, charities, biotech.

– Having a commitment to peer review

– Building an independent scientific expert panel with expertise in emerging technologies

– Funding research into treatments for all types of epidermolysis bullosa

 

“What Cure EB has done for research into EB is nothing short of amazing. What it needed was a driver and a focus, and Cure EB is pushing the accelerator to the floor.”

– Professor McGrath, Professor of Molecular Dermatology, King’s College Hospital, Guy’s and St Thomas’s Hospital

Professor McGrath

Research policy

There is strong public support for medical research charities to find new treatments and cures for debilitating and  life threatening conditions. This research will use a variety of different strategies to achieve this these aims.

To include

Cultured cells grown in labs, tissue samples, computer models, skin equivalents and when appropriate, animals. Clinical trials may include volunteers

 

The decision to use animals is not taken lightly, but there instances when it necessary to use animal models. Typically this is where the benefits to the health of patients outweighs any harm to animals. There are strict laws governing their welfare and use both in the UK and other countries where our research is carried out. Our research adheres to the AMRC principles of refine, reduce and replace.


AMRC use of animals in medical research 

 

 

Damian Lewis talking to Professor John McGrath

 

Search this site
Follow us